The aim of the present study is to investigate the impact of organizational and human factors on human resource productivity with the mediating role of agility factors (case study: North Drilling Company). In this regard, the concepts of human resources, productivity, and agility were reviewed, and the structural equation modeling (SEM) method was employed to examine the impact of organizational and human factors on human resource productivity with the mediating role of agility factors. The study population includes all employees of the North Drilling Company. The sample size was determined to be 333 individuals using Cochran's formula based on the statistical population. A questionnaire was used for data collection, whose validity was confirmed through content validity by experts, and construct validity and structure were verified through confirmatory factor analysis (CFA) using SmartPLS software. The reliability was assessed and confirmed using Cronbach's alpha coefficient and composite reliability (CR) in SPSS software. For data analysis, the Kolmogorov-Smirnov test was used to check normality, and CFA and SEM were employed to test hypotheses and validate the model. The results indicated that human and organizational factors influence organizational agility, which in turn enhances the level of organizational agility strategies and, consequently, improves employee productivity. Furthermore, the findings revealed that agility drivers and challenges in human resource management influence productivity through agility strategies.